HIF2 and endocrine neoplasia: an evolving story.
نویسنده
چکیده
In this issue of Endocrine-Related Cancer, Toledo et al. report the identification of activating mutations in the HIF2 (EPAS1) transcription factor in a subset of sporadic pheochromocytomas and paragangliomas. These findings add significantly to an evolving and complex story of the role of hypoxic gene response pathways in human endocrine neoplasia.
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ورودعنوان ژورنال:
- Endocrine-related cancer
دوره 20 3 شماره
صفحات -
تاریخ انتشار 2013